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Filtered Search Results
eMolecules 4,6-Dichloro-N-methylpyrimidin-2-amine | 10397-15-6 | MFCD02091109 | 1g
Ambeed | 4,6-Dichloro-N-methylpyrimidin-2-amine | 1g | 490490782 | A105522 | | 10397-15-6 | MFCD02091109 | 178.020 | C5H5Cl2N3
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eMolecules Ambeed / (Bromoethynyl)benzene / 100mg / 570568411 / A197823 / / 932-87-6 / MFCD00015715 / 181.032 / C8H5Br
Ambeed / (Bromoethynyl)benzene / 100mg / 570568411 / A197823 / / 932-87-6 / MFCD00015715 / 181.032 / C8H5Br
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![Medchemexpress LLC N-[3-(1H-indol-4-yl)-5-(2-methoxypyridine-4-carbonyl)phenyl]methanesulfonamide | 915412-67-8 | MFCD18782727 | 99.9% | C22H19N3O4S | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261632.png-250.jpg)
Medchemexpress LLC N-[3-(1H-indol-4-yl)-5-(2-methoxypyridine-4-carbonyl)phenyl]methanesulfonamide | 915412-67-8 | MFCD18782727 | 99.9% | C22H19N3O4S | 10MG
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LP-261 is an orally active antimitotic small-molecule research compound that inhibits tubulin polymerization and has demonstrated in vivo efficacy against human non-small-cell lung tumor xenografts. It is supplied as a high-purity solid and is documented with analytical files for research use.
- Inhibits tubulin polymerization (EC50 3.2 μM).
- Demonstrated in vivo antitumor activity in xenograft models.
- High purity solid with available COA, LC-MS, and SDS documentation.
- Molecular formula C22H19N3O4S; molecular weight 421.47 g·mol⁻¹.
- Soluble in DMSO (≈33.33 mg/mL) for stock solution preparation.
- Storage recommendations provided for powder and solution formats.
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eMolecules 2-Hydroxy-4-methylpyrimidine-5-carboxylic acid | 13008-17-8 | MFCD03425969 | 1g
Combi-Blocks, Inc. | 2-Hydroxy-4-methylpyrimidine-5-carboxylic acid | 1g | 603137339 | QC-4927 | 95.000 | 13008-17-8 | MFCD03425969 | 154.125 | C6H6N2O3
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Medchemexpress LLC SSAA09E2 | 883944-52-3 | 98.37% | 300.36 | 50 MG
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SSAA09E2 is an inhibitor of SARS-CoV (Severe acute respiratory syndrome-Coronavirus) replication. It functions by blocking early interactions between SARS-S and the SARS-CoV receptor, Angiotensin Converting Enzyme-2 (ACE2). This product is intended for research use only.
- Inhibits SARS-CoV replication
- Blocks early interactions between SARS-S and ACE2 receptor
- IC50 (SARS-CoV): 3.1 μM
- CC50 (HEK-293T): > 100 μM
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Medchemexpress LLC LP-261 | 915412-67-8 | 99.9% | C22H19N3O4S | 50 MG
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LP-261 is a potent, orally active anti-mitotic agent that inhibits tubulin polymerization in vitro with an EC50 of 3.2 μM. It has shown the ability to inhibit the growth of human non-small-cell lung tumors (NCI-H522) in vivo and is used in cancer research.
- Potent and orally active anti-mitotic agent.
- Inhibits tubulin polymerization in vitro.
- Shows potent G2/M block activity in various cell lines (MCF-7, H522, Jurkat, SW-620, BXPC-3, and PC-3) with IC50 values ranging from 0.01 μM to 0.38 μM.
- Effectively inhibits tumor growth in a human non-small-cell lung tumor xenograft model in NCr-nu mice, with a 96% reduction in mean tumor volume at 50 mg/kg.
- Displays rapid oral adsorption with a Tmax of 2.0 hours in rats.
- Exhibits moderate elimination rate with a terminal half-life of 1.4 hours in rats.
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eMolecules AstaTech / 4-O-TOLYLPIPERIDINE / 0.25g / 268503647 / BL008747 / 95.000 / 630116-52-8 / MFCD05189913 / 175.275 / C12H17N
AstaTech / 4-O-TOLYLPIPERIDINE / 0.25g / 268503647 / BL008747 / 95.000 / 630116-52-8 / MFCD05189913 / 175.275 / C12H17N
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![eMolecules Pharmablock / [3-(trifluoromethyl)-1-bicyclo[1.1.1]pentanyl]methanaminehydrochloride / 25mg / 714320303 / PB93851-1 / 0.000 / 1886967-52-7 / [null] / 201.620 / C7H11ClF3N](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502461570.JPG-250.jpg)
eMolecules Pharmablock / [3-(trifluoromethyl)-1-bicyclo[1.1.1]pentanyl]methanaminehydrochloride / 25mg / 714320303 / PB93851-1 / 0.000 / 1886967-52-7 / [null] / 201.620 / C7H11ClF3N
Pharmablock / [3-(trifluoromethyl)-1-bicyclo[1.1.1]pentanyl]methanaminehydrochloride / 25mg / 714320303 / PB93851-1 / 0.000 / 1886967-52-7 / [null] / 201.620 / C7H11ClF3N
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![eMolecules Pharmablock / ethyl imidazo[12-a]pyrazine-2-carboxylate / 25mg / 551139039 / PBN20121183 / 0.000 / 77112-52-8 / MFCD08460079 / 191.190 / C9H9N3O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502517640.JPG-250.jpg)
eMolecules Pharmablock / ethyl imidazo[12-a]pyrazine-2-carboxylate / 25mg / 551139039 / PBN20121183 / 0.000 / 77112-52-8 / MFCD08460079 / 191.190 / C9H9N3O2
Pharmablock / ethyl imidazo[12-a]pyrazine-2-carboxylate / 25mg / 551139039 / PBN20121183 / 0.000 / 77112-52-8 / MFCD08460079 / 191.190 / C9H9N3O2
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Medchemexpress LLC 1-((1H-indazol-5-yl)sulfonyl)-N-ethyl-N-(2-(trifluoromethyl)benzyl)piperidine-4-carboxamide | 1627138-52-6 | >99.0% | 494.53 g/mol | C23H25F3N4O3S | 100MG
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ML380 is a potent, brain-penetrant positive allosteric modulator (PAM) of the M5 muscarinic acetylcholine receptor used in research on GPCR signaling and neuronal function. It increases acetylcholine affinity at M5 and displays subtype selectivity (EC50 human ≈190 nM; rat ≈610 nM). CAS: 1627138-52-6.
- Potent positive allosteric modulator of M5 mAChR.
- Subtype-selective with moderate selectivity over M1 and M3.
- Brain-penetrant, suitable for in vivo pharmacology studies.
- High purity (>99.0% by HPLC).
- Molecular formula C23H25F3N4O3S; molecular weight 494.53 g/mol.
- Supplied as a 100 mg solid for research use only.
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![eMolecules AstaTech / 2-AMINO-4-HYDROXYPYRIMIDINE-5-CARBOXAMIDE / 0.25g / 686066854 / E79787 / 95.000 / 857200-61-4 / [null] / 154.129 / C5H6N4O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502475377.JPG-250.jpg)
eMolecules AstaTech / 2-AMINO-4-HYDROXYPYRIMIDINE-5-CARBOXAMIDE / 0.25g / 686066854 / E79787 / 95.000 / 857200-61-4 / [null] / 154.129 / C5H6N4O2
AstaTech / 2-AMINO-4-HYDROXYPYRIMIDINE-5-CARBOXAMIDE / 0.25g / 686066854 / E79787 / 95.000 / 857200-61-4 / [null] / 154.129 / C5H6N4O2
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eMolecules Broadpharm / Biotin-LC-LC-NHS Ester / 50mg / 279709298 / BP-22110 / 97.000 / 89889-52-1 / MFCD00467154 / 567.700 / C26H41N5O7S
Broadpharm / Biotin-LC-LC-NHS Ester / 50mg / 279709298 / BP-22110 / 97.000 / 89889-52-1 / MFCD00467154 / 567.700 / C26H41N5O7S
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eMolecules Medchem Express / PKA-IN-1 / 25mg / 779715053 / HY-115732 / / 179985-52-5 / MFCD04039368 / 225.251 / C13H11N3O
Medchem Express / PKA-IN-1 / 25mg / 779715053 / HY-115732 / / 179985-52-5 / MFCD04039368 / 225.251 / C13H11N3O
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Medchemexpress LLC Me1111 | 1391758-52-3 | 100.0% | 202.25 g/mol | C12H14N2O | 100 MG
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ME1111 is an antifungal small molecule (CAS 1391758-52-3) that inhibits succinate dehydrogenase in Trichophyton species. It is active against dermatophytes and is provided for research use in antifungal and onychomycosis studies, with validated solubility and storage guidelines for in vitro and in vivo applications.
- Antifungal activity against dermatophytes.
- Inhibits succinate dehydrogenase in Trichophyton species.
- High reported purity (99.95%).
- Soluble in DMSO at 100 mg/mL for in vitro use.
- Powder storage: -20°C for long-term stability.
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eMolecules N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide | 456-12-2 | MFCD00048045 | 1g
Ambeed | N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide | 1g | 525098457 | A181072 | | 456-12-2 | MFCD00048045 | 297.354 | C18H19NO3
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